NFL Week 10 Picks vs. Spread, Tips & Predictions

Posted at 12:27 pm Wednesday, November 6, 2024

What’s the best ATS bet to make considering each of the 14 games on the NFL’s Week 10 schedule? Our favorite pick against the spread is the Cardinals -1, but we have many more suggestions for you that could lead to the betting opportunities below.

Find an edge over the competition and take advantage of our NFL picks. BetMGM contains all the information you need to start betting on the NFL.

NFL Picks vs. Spread – Week 10

Go to match:

Pick: Cardinals -1 vs. Jets

Match-up: New York Jets – Arizona Cardinals
Predicted winner and margin: Cardinals by 11.7 points (Bet on this game at BetMGM)
Spreading: Cardinals -1
Time: 4:25 pm ET
Date: November 10
TV channel: CBS
Live broadcast: Paramount+ | Fubo (Local restrictions may apply)

Pick: Rams -2.5 vs. Dolphins.

Match-up: Miami Dolphins – Los Angeles Rams
Predicted winner and margin: Rams by 16.7 points (Bet on this game at BetMGM)
Spreading: Rams -2.5
Time: 8:15 pm ET
Date: November 11
TV channel: ESPN
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Commanders 3 vs. Steelers.

Match-up: Pittsburgh Steelers – Washington Commanders
Predicted winner and margin: Commanders by 4.7 points (Bet on this game at BetMGM)
Spreading: Commanders -3
Time: 1:00 p.m. Eastern Time
Date: November 10
TV channel: CBS
Live broadcast: Paramount+ | Fubo (Local restrictions may apply)

Pick: Falcons -3.5 vs. Saints.

Match-up: Atlanta Falcons – New Orleans Saints
Predicted winner and margin: Falcons by 5.3 points (Bet on this game at BetMGM)
Spreading: Falcons -3.5
Time: 1:00 p.m. Eastern Time
Date: November 10
TV channel: FOX
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Lions -3.5 vs. Texans

Match-up: Detroit Lions – Houston Texans
Predicted winner and margin: Lviv with a difference of 8.3 points (Bet on this game at BetMGM)
Spreading: Lions -3.5
Time: 8:20 pm ET
Date: November 10
TV channel: NBK
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Bills 4 vs. Colts.

Match-up: Buffalo Bills at Indianapolis Colts
Predicted winner and margin: Bills by 5.9 points (Bet on this game at BetMGM)
Spreading: Accounts -4
Time: 1:00 p.m. Eastern Time
Date: November 10
TV channel: CBS
Live broadcast: Paramount+ | Fubo (Local restrictions may apply)

Pick: Vikings 4 vs. Jaguars

Match-up: Minnesota Vikings – Jacksonville Jaguars
Predicted winner and margin: Vikings by 14.9 points (Bet on this game at BetMGM)
Spreading: Vikings -4
Time: 1:00 p.m. Eastern Time
Date: November 10
TV channel: FOX
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Buccaneers +5.5 vs. 49ers

Match-up: San Francisco 49ers – Tampa Bay Buccaneers
Predicted winner and margin: Buccaneers by 10.0 points (Bet on this game at BetMGM)
Spreading: 49ers -5.5
Time: 1:00 p.m. Eastern Time
Date: November 10
TV channel: FOX
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Giants 6 vs. Panthers.

Match-up: New York Giants vs Carolina Panthers
Predicted winner and margin: Giants by 7.3 points (Bet on this game at BetMGM)
Spreading: Giants -6
Time: 9:30 am ET
Date: November 10
TV channel: NFL Network
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Bears -6 vs. Patriots.

Match-up: New England Patriots – Chicago Bears
Predicted winner and margin: Bears by 13.6 points (Bet on this game at BetMGM)
Spreading: Bears -6
Time: 1:00 p.m. Eastern Time
Date: November 10
TV channel: FOX
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Ravens -6.5 vs. Bengals

Match-up: Cincinnati Bengals – Baltimore Ravens
Predicted winner and margin: Ravens by 14.1 points (Bet on this game at BetMGM)
Spreading: Crows -6.5
Time: 8:15 pm ET
Date: November 7
TV channel: Amazon Prime Video
Live broadcast: Watch this game on Prime Video (Local restrictions may apply)

Pick: Chargers -7.5 vs. Titans.

Match-up: Tennessee Titans – Los Angeles Chargers
Predicted winner and margin: Chargers at 19.6 points (Bet on this game at BetMGM)
Spreading: Chargers -7.5
Time: 4:05 pm ET
Date: November 10
TV channel: FOX
Live broadcast: Check out this game on Fubo (Local restrictions may apply)

Pick: Eagles -7.5 vs. Cowboys.

Match-up: Philadelphia Eagles – Dallas Cowboys
Predicted winner and margin: Eagles by 8.3 points (Bet on this game at BetMGM)
Spreading: Eagles -7.5
Time: 4:25 pm ET
Date: November 10
TV channel: CBS
Live broadcast: Paramount+ | Fubo (Local restrictions may apply)

Pick: Chiefs -8.5 vs. Broncos.

Match-up: Denver Broncos – Kansas City Chiefs
Predicted winner and margin: The Chiefs are by 9.3 points (Bet on this game at BetMGM)
Spreading: Managers -8.5
Time: 1:00 p.m. Eastern Time
Date: November 10
TV channel: CBS
Live broadcast: Paramount+ | Fubo (Local restrictions may apply)

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